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Author:

Geathers, Jasmine

Title:

Development of a Rapid and Clinically Relevant Model of AMD

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Hyperreflective Foci
AMD
R345W fibulin-3
Sodium Iodate
Retinal Degeneration

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Committee Members:

Salvatore Stella, Major Field Member
Ralph Keil, Program Head/Chair
John Hulleman, Special Member
Vladimir Spiegelman, Outside Unit & Field Member
Jeffrey Sundstrom, Chair & Dissertation Advisor
James Connor, Dissertation Co-Advisor

Author:

Bricker, Kristen

Title:

MIR-21 REGULATION OF SYSTEMIC AUTOIMMUNITY AND IMMUNITY

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

B cells
Autoimmunity
Germinal Center
Antibody
Infection
Influenza
Plasma Cells
miRNA

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Committee Members:

Aron Lukacher, Major Field Member
Ziaur Rahman, Chair & Dissertation Advisor
Todd Schell, Major Field Member
Zissis Chroneos, Outside Unit & Field Member
Ralph Keil, Program Head/Chair
Aron Eliot Lukacher, Special Member
S. Rameeza Allie, Major Field Member

Author:

Shenoy, Ganesh

Title:

The Role of Iron in Glioblastoma

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

glioblastoma
iron

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Committee Members:

Jeffrey Sundstrom, Outside Unit & Field Member
James Connor, Chair & Dissertation Advisor
Todd Schell, Major Field Member
Zissis Chroneos, Major Field Member
Ralph Keil, Program Head/Chair
Sheldon Holder, Special Member

Author:

Crawford, Lataijah

Title:

Characterization Of Decursinol Efficacy, Tolerance, And Mechanism In Models Of Pain

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

AGN; Angelica gigas Nakai
DOH; Decursinol
CENP; Chemotherapy-evoked neuropathic pain
MOR; Morphine
NXO; Naloxone
TRPA1; Transient receptor potential ankyrin 1
TRPV1
Transient receptor vanilloid receptor 1
TRPV1; Transient receptor vanilloid receptor 1
5-HT2; Serotonin receptor 2
5-HT2A; Serotonin receptor 2A
5-HT2C; Serotonin receptor 2C
CB1; Cannabinoid receptor type 1
CB2; Cannabinoid receptor type 2
WT; Wild-type mouse

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Committee Members:

Junxuan Lu, Outside Field Member
Patricia Grigson Kennedy, Outside Unit Member
Ralph Keil, Program Head/Chair
John Ellis, Major Field Member
Daniel Morgan, Special Member
Lisa Shantz, Chair & Dissertation Advisor

Author:

Liu, Xiaoming

Title:

Mechanisms of resistance to anti-GD2 immunotherapy in neuroblastoma

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Neuroblastoma
Small extracellular vesicles
Tumor microenvironment
NK cells
anti-GD2 immunotherapy
CRISPR screen

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Committee Members:

Vladimir Spiegelman, Major Field Member
Jeffrey Sundstrom, Outside Unit Member
Hong-Gang Wang, Chair & Dissertation Advisor
Todd Schell, Major Field Member
Edward Harhaj, Outside Field Member
Ralph Keil, Program Head/Chair

Author:

Walston, Joshua

Title:

Epstein-Barr virus Glycoproteins BDLF2 and BMRF2 are Important for Efficient Infection and Spread in Oral Epithelia

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

EBV
BDLF2
BMRF2
Cell-to-cell
Stratified Epithelium
Herpesvirus

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Committee Members:

Ralph Keil, Program Head/Chair
Neil Christensen, Major Field Member
Gregory Yochum, Outside Unit & Field Member
Jianming Hu, Major Field Member
Jeffery Sample, Major Field Member
Clare Sample, Chair & Dissertation Advisor

Author:

Hong, Xupeng

Title:

Determinants of HBV Host Tropism and Roles of HBV Precore/Core Proteins

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Hepatitis B Virus
HBV
host tropism
core protein
precore protein
Woodchuck Hepatitis Virus
capsid
cccDNA
infection
replication

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Committee Members:

Jianming Hu, Chair & Dissertation Advisor
John Wills, Major Field Member
Edward Harhaj, Major Field Member
Craig Meyers, Major Field Member
Fang Tian, Outside Unit & Field Member
Ralph Keil, Program Head/Chair
Yuka Imamura Kawasawa, Special Member

Author:

Maglakelidze, Natella

Title:

Role of autoimmune regulator (AIRE) in keratinocyte biology and skin diseases

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Autoimmune regulator
Alopecia Areata
Mouse model
Hair follicle biology
Keratinocyte biology
JAK-STAT signaling
Vitiligo

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Committee Members:

David Degraff, Outside Unit Member
Amanda Nelson, Major Field Member
Ryan Hobbs, Co-Chair & Dissertation Advisor
Joslyn R Sciacca Kirby, Special Member
Lisa Shantz, Co-Chair & Outside Field Member
Ralph Keil, Program Head/Chair

Author:

Kendra, Christopher

Title:

A Salmonella Virulence Factor Regulates Second Messenger Signaling and Effector Protein Expression via Proteolysis

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Salmonella
Proteolysis
Cellulose
second messenger
virulence factors

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Committee Members:

Christopher Norbury, Major Field Member
Mauricio Pontes, Co-Chair & Dissertation Advisor
Guy Townsend, Outside Unit Member
Clare Sample, Co-Chair & Outside Field Member
Ralph Keil, Program Head/Chair

Author:

Heebner, Jessica

Title:

Visual Proteomics of Neuronal Growth Cones: Deep Learning Segmentation for Large Scale Analysis of Cryo-Electron Tomograms

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

cryoEM
cryoET
Deep Learning
Image Segmentation
Growth Cones
Proteomics
Actin
Cofilactin
TriC/CCT
Tomography

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Committee Members:

David Degraff, Co-Chair & Outside Field Member
Richard Mailman, Outside Unit Member
Matthew Swulius, Chair & Dissertation Advisor
Maria Bewley, Major Field Member
Fang Tian, Major Field Member
Lisa Shantz, Program Head/Chair