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Start Over Graduate Program Molecular, Cellular and Integrative Biosciences Year 2016

1. Evaluation of whole exome sequencing technology in cohort dataset and quantification of phenotypic alterations in a model organism

open_access
Open Access
Author:
Wang, Qingyu
Title:
Evaluation of whole exome sequencing technology in cohort dataset and quantification of phenotypic alterations in a model organism
Graduate Program:
Molecular, Cellular and Integrative Biosciences
Keywords:
Whole Exome Sequencing
low coverage
unevenness
Drosophila melanogaster
eye phenotype
image processing
quantitative assessment
File:
Download QWFinal_dissertation.pdf
Committee Members:
Naomi S Altman, Dissertation Advisor/Co-Advisor
Santhosh Girirajan, Dissertation Advisor/Co-Advisor
Ross Cameron Hardison, Committee Member
Shaun A Mahony, Committee Member
Cooduvalli S Shashikant, Committee Member

2. Developing hippocampal delivery of AAV-NeuroD1 as a novel therapy for Alzheimer's disease

open_access
Open Access
Author:
Wang, Fan
Title:
Developing hippocampal delivery of AAV-NeuroD1 as a novel therapy for Alzheimer's disease
Graduate Program:
Molecular, Cellular and Integrative Biosciences
Keywords:
Alzheimer's disease
NeuroD1
hippocampus
AAV
File:
Download 1-Thesis-Fan_Wang-final2.pdf
Committee Members:
Gong Chen, Thesis Advisor/Co-Advisor
Bernhard Luscher, Thesis Advisor/Co-Advisor
Richard W Ordway, Thesis Advisor/Co-Advisor
Yingwei Mao, Thesis Advisor/Co-Advisor

3. Understanding mitochondrial DNA and RNA variability in humans

open_access
Open Access
Author:
Rebolledo Jaramillo, Boris Eduardo
Title:
Understanding mitochondrial DNA and RNA variability in humans
Graduate Program:
Molecular, Cellular and Integrative Biosciences
Keywords:
mitochondria
heteroplasmy
germ-line bottleneck
mitochondrial RNA
mtDNA
File:
Download ber5099_IBIOS-BG_dissertation_2016.pdf
Committee Members:
Anton Nekrutenko, Dissertation Advisor/Co-Advisor
Kateryna Dmytrivna Makova, Committee Member
Francesca Chiaromonte, Committee Member
Michael Degiorgio, Committee Member

5. THE REGULATION OF ER CHAPERONES AND PROINSULIN PROTEOSTASIS BY PERK EIF2ALPHA KINASE

open_access
Open Access
Author:
Lewis, Carrie Rebekah
Title:
THE REGULATION OF ER CHAPERONES AND PROINSULIN PROTEOSTASIS BY PERK EIF2ALPHA KINASE
Graduate Program:
Molecular, Cellular and Integrative Biosciences
Keywords:
proinsulin
ER chaperones
PERK
EIF2AK3
File:
Download CL_Thesis_Dissertation_FINAL_edited_with_corrections_7-14-16.pdf
Committee Members:
Douglas Cavener, Dissertation Advisor/Co-Advisor
Melissa Rolls, Committee Chair/Co-Chair
Zhi-Chun Lai, Committee Member
Douglas Cavener, Committee Member
Yanming Wang, Outside Member

6. STUDY OF GROWTH OF STRESS ERYTHROID PROGENITORS FROM PERIPHERAL BLOOD MONONUCLEAR CELLS IN MURINE AND HUMAN ANEMIC MODEL SYSTEMS.

open_access
Open Access
Author:
Hariharan, Sneha
Title:
STUDY OF GROWTH OF STRESS ERYTHROID PROGENITORS FROM PERIPHERAL BLOOD MONONUCLEAR CELLS IN MURINE AND HUMAN ANEMIC MODEL SYSTEMS.
Graduate Program:
Molecular, Cellular and Integrative Biosciences
Keywords:
Stress erythropoiesis
erythroid progenitor migration
Sickle cell disease
acute anemia
File:
Download Sneha_Masters_Thesis_2016.pdf
Committee Members:
Robert Paulson, Thesis Advisor/Co-Advisor
K. Sandeep Prabhu, Committee Member
Pamela A. Hankey, Committee Member

7. A NOVEL SMALL MOLECULE DNA INTERCALATOR PZ1225 IN CANCER CELL APOPTOSIS AND A HISTONE MODIFIER PAD4 IN MACROPHAGE EXTRACELLULAR TRAP FORMATION

open_access
Open Access
Author:
sun, jinquan
Title:
A NOVEL SMALL MOLECULE DNA INTERCALATOR PZ1225 IN CANCER CELL APOPTOSIS AND A HISTONE MODIFIER PAD4 IN MACROPHAGE EXTRACELLULAR TRAP FORMATION
Graduate Program:
Molecular, Cellular and Integrative Biosciences
Keywords:
DNA damage
DNA intercalator
small molecule
MAPK
mTOR
apoptosis
macrophage
extracellular traps
PAD4
citrullination
stroke
File:
Download Graduation_Thesis-Jinquan-20161201.pdf
Committee Members:
Yanming Wang, Dissertation Advisor/Co-Advisor
Zhi-Chun Lai, Committee Chair/Co-Chair
Douglas Cavener, Committee Member
Lu Bai, Committee Member
Robert Paulson, Outside Member

8. A novel mouse model with neuroligin-2 R215H mutation for the study of psychiatric disorders

open_access
Open Access
Author:
Jiang, Dongyun
Title:
A novel mouse model with neuroligin-2 R215H mutation for the study of psychiatric disorders
Graduate Program:
Molecular, Cellular and Integrative Biosciences
Keywords:
neuroligin 2
R215H mutation
schizophrenia
psychiatric disorders
GABAergic deficits
File:
Download PS-Thesis-Dongyun_Jiang.pdf
Committee Members:
Gong Chen, Dissertation Advisor/Co-Advisor
Gong Chen, Committee Chair/Co-Chair
Bernhard Luscher, Committee Member
Yingwei Mao, Committee Member
Nanyin Zhang, Outside Member
Aimin Liu, Committee Member