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Author:

Basile, Anna Okula

Title:

CONTINUING TO SEARCH FOR THE MISSING HERITABILITY USING BIOLOGICALLY-INSPIRED AND DATA-DRIVEN APPROACHES

Graduate Program:

Biochemistry, Microbiology, and Molecular Biology

Keywords:

human genetics
complex disease
machine learning
informatics
pattern recognition
rare variants
missing heritability

File:

Download Basile_PhD_Dissertation_Revisions_Final_022118.pdf

Committee Members:

Marylyn Deriggi Ritchie, Dissertation Advisor/Co-Advisor
Marylyn Deriggi Ritchie, Committee Chair/Co-Chair
Santhosh Girirajan, Committee Member
Ross Cameron Hardison, Committee Member
George H Perry, Outside Member

Author:

Salameh, Tarik

Title:

Chromatin loop detection via machine learning on genome-wide contact data

Graduate Program:

Bioinformatics and Genomics

Keywords:

machine learning
chromatin looping
3dgenomics
supervised learning
genome-wide contact map
Hi-C
loop extrusion

File:

Download dissertation_salamehf.pdf

Committee Members:

Feng Yue, Dissertation Advisor/Co-Advisor
Robert G Levenson, Dissertation Advisor/Co-Advisor
Aron Eliot Lukacher, Outside Member
Robert G Levenson, Committee Chair/Co-Chair
Shaun Mahony, Committee Member
Gary A Thomas, Special Member
George H Perry, Program Head/Chair
Feng Yue, Committee Chair/Co-Chair

Author:

Hughey, Jordan

Title:

In-silico modeling gene expression utilizing genomic activity and 3D contact information

Graduate Program:

Bioinformatics and Genomics (PhD)

Keywords:

gene regulation
transcriptome
association studies
machine learning
epigenomics
epigenetics

File:

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Committee Members:

Dajiang Liu, Chair & Dissertation Advisor
Shaun Mahony, Major Field Member
James Broach, Outside Unit & Field Member
Santhosh Girirajan, Major Field Member
George H Perry, Program Head/Chair