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Author:

Manzano Garcia, Jesus

Title:

Therapeutic grade RNA purification by ultrafiltration

Graduate Program:

Chemical Engineering

Keywords:

Nucleic Acids
Purification
Ultrafiltration

File:

Download Ivan_Manzano-Dissertation_rev.pdf

Committee Members:

Andrew Zydney, Dissertation Advisor/Co-Advisor
Andrew Zydney, Committee Chair/Co-Chair
Themis Matsoukas, Committee Member
Hee Jeung Oh, Committee Member
William O Hancock, Outside Member
Phillip E Savage, Program Head/Chair

Author:

Tang, Wanjian

Title:

Impact of Cardiomyopathy Mutations and Small Molecule Drugs on the Structural and Functional Properties of Human Beta-Cardiac Myosin

Graduate Program:

Biomedical Sciences

Keywords:

Myosin
Inherited cardiomyopathies
Omecamtiv mecarbil
para-Nitroblebbistatin
Cardiac muscle
Structural kinetics

File:

Download Dissertation_Wanjian_Tang_final.pdf

Committee Members:

Christopher Martin Yengo, Dissertation Advisor/Co-Advisor
Christopher Martin Yengo, Committee Chair/Co-Chair
William O Hancock, Committee Member
Edward B Lankford, Committee Member
Thomas E Spratt, Outside Member
Ira Joseph Ropson, Committee Member
Ralph Lauren Keil, Program Head/Chair

Author:

Shi, Xuechen

Title:

Mechanical forces regulate tissue morphologies

Graduate Program:

Bioengineering

Keywords:

Interfacial tension
Tissue morphology
Mechanical stretch
Traction force

File:

Download Dissertation_XS.pdf

Committee Members:

Sulin Zhang, Dissertation Advisor/Co-Advisor
Sulin Zhang, Committee Chair/Co-Chair
William O Hancock, Committee Member
Pak Kin Wong, Committee Member
Lauren Dell Zarzar, Outside Member
Daniel J Hayes, Program Head/Chair

Author:

Haviland, Zachary

Title:

Lignin impairs Cel7A degradation of cellulose by impeding enzyme movement and not by acting as a sink

Graduate Program:

Biomedical Engineering (MS)

Keywords:

cellulose
lignin
Cel7A
single-molecule microscopy
biofuel

File:

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Committee Members:

William O Hancock, Thesis Advisor/Co-Advisor
Justin R Pritchard, Committee Member
Daniel Hayes, Program Head/Chair
Howard M Salis, Committee Member

Author:

Luque, Miranda

Title:

THE EFFECT OF pH ON THE INTERACTIONS OF KINESIN-1 AND KINESIN-2 WITH THEIR MICROTUBULE TRACK

Graduate Program:

Integrative and Biomedical Physiology (MS)

Keywords:

pH
microtubule
kinesin-1
kineisn-2

File:

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Committee Members:

Donna Korzick, Program Head/Chair
William O Hancock, Thesis Advisor/Co-Advisor
Connie Jo Rogers, Committee Member
Gustavo Alberto Nader, Committee Member

Author:

Torab, Peter

Title:

Collective Invasion In Heterogeneous Bladder Cancer Tumors: A Biomanufacturing Approach

Graduate Program:

Mechanical Engineering

Keywords:

bladder
cancer
heterogeneity
invasion
heterogeneous
biomanufacturing
biosensor
biomanufactured
biomanufacture
3D
extracellular matrix
leader cells
collective invasion
invasion assay
in vitro

File:

Download Peter_Torab_Dissertation.pdf

Committee Members:

Pak Kin Wong, Dissertation Advisor/Co-Advisor
Pak Kin Wong, Committee Chair/Co-Chair
Jing Du, Committee Member
Tak Sing Wong, Committee Member
William O Hancock, Outside Member
Daniel Connell Haworth, Program Head/Chair

Author:

Hospodiuk, Monika

Title:

ENGINEERING OF NEOVASCULARIZED-PANCREAS-ON-A-CHIP MODEL

Graduate Program:

Biorenewable Systems

Keywords:

pancreas
vascularization
organ on a chip
tissue engineering
ECM
perfusion
hydrogel
3D bioprinting

File:

Download PhD_Dissertation_20190412_FINAL3.pdf

Committee Members:

Jeffrey M Catchmark, Dissertation Advisor/Co-Advisor
Jeffrey M Catchmark, Committee Chair/Co-Chair
Ibrahim Tarik Ozbolat, Committee Chair/Co-Chair
Paul Heinz Heinemann, Committee Member
William O Hancock, Outside Member
Nicole Brown, Committee Member

Author:

Risbud, Aneesh

Title:

Bio-hybrid spheroids through cell-mediated microgel self assembly

Graduate Program:

Biomedical Engineering (MS)

Keywords:

GelMA
Spheroids
Bio-hybrid
Cell assembly

File:

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Committee Members:

Amir Sheikhi, Thesis Advisor/Co-Advisor
Spencer Szczesny, Committee Member
Daniel Hayes, Program Head/Chair
William O Hancock, Committee Member

Author:

Govindarajan, Maalavika

Title:

Mechanisms that influence microtubule nucleation machinery localization in Drosophila melanogaster dendritic branchpoints

Graduate Program:

Neuroscience (MS)

Keywords:

microtubule
nucleation
Drosophila melanogaster
neurons
dendritic branchpoints
cytoskeleton
cell biology
confocal microscopy

File:

Download MS_Thesis-_PSU-Final-_Maalavika_Govindarajan.pdf

Committee Members:

Melissa Rolls, Thesis Advisor/Co-Advisor
Aimin Liu, Committee Member
Sonia Cavigelli, Professor in Charge/Director of Graduate Studies
William O Hancock, Committee Member