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Author:

Yau, Eric

Title:

Role of Surfactant Protein A and its Receptor SP-R210 in Influenza Responses in Macrophages

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Surfactant Protein
SP-A
Macrophages
Alveolar Macrophages
Influenza
IAV
Trafficking
Pulmonary Immunity
Pulmonary Inflammation
Surfactant Protein
SP-A
Alveolar Macrophage
Macrophage
AM
Influenza
Influenza A
IAV
Pulmonary Immunity
Pulmonary Inflammation
Trafficking
Virus Trafficking
IAV Trafficking
IAV Endocytosis
Surfactant Protein A

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Committee Members:

Jong Yun, Outside Unit & Field Member
Nicholas Buchkovich, Major Field Member
John Wills, Major Field Member
Zissis Chroneos, Chair & Dissertation Advisor
Ralph Keil, Program Head/Chair

Author:

Miller, William

Title:

The Role Of Regulated In Development and DNA Damage Response 1 (REDD1) in Diabetes-Induced Retinal Pathology and Visual Dysfunction

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

antioxidants
diabetes
oxidative stress
retina
vision
glycogen glycogen synthase kinase 3 (GSK-3)
hyperglycemia
nuclear factor 2 (erythroid-derived 2-like factor) (NFE2L2) (Nrf2)
oxidative stress; post-translational modification (PTM)
reactive oxygen species (ROS)
retinopathy
chaperone mediated autophagy (CMA)

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Committee Members:

Alistair Barber, Outside Unit & Field Member
Jeffrey Sundstrom, Major Field Member
Scot Kimball, Major Field Member
David Waning, Major Field Member
Michael Dennis, Chair & Dissertation Advisor
Ralph Keil, Program Head/Chair

Author:

Wang, Ernest Weider

Title:

Pathologic Substrates of Quantitative Magnetic Resonance Imaging in Parkinsonisms

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

MRI
parkinsonisms
pathology
neuropathology
gene-environment
pesticides
paraquat
HFE
susceptibility MRI
DTI
substantia nigra
iron
Parkinson's disease
progressive supranuclear palsy
multiple system atrophy
corticobasal degeneration
dopamine
movement disorders
neurology
brain

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Committee Members:

Xuemei Huang, Chair & Dissertation Advisor
Guangwei Du, Major Field Member
Gary Perdew, Outside Unit & Field Member
James Connor, Major Field Member
Matthew Coates, Special Member
Ralph Keil, Program Head/Chair

Author:

Baraniak, James

Title:

REVEALING THE ORAI-STIM BINDING INTERFACE THROUGH THE USE OF NOVEL PEPTIDES

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

calcium
store-operated calcium entry
soce
calcium homeostasis
STIM
Orai
Calcium channels
M4x peptide
peptide modulation
Orai binding interface
SOAR
stormorken
signal transduction
NFAT
pan-specific inhibition
stim-orai interacting interface

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Committee Members:

Salvatore Stella, Outside Unit Member
Thomas Spratt, Outside Field Member
Christopher Yengo, Major Field Member
Donald Gill, Chair & Dissertation Advisor
Ralph Keil, Program Head/Chair

Author:

Lauver, Matthew

Title:

The Role of Polyomavirus Capsid Mutations in Antibody Evasion and Virulence

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Polyomavirus
Antibody Evasion
Virus Capsid Mutations
Viral Pathogenesis
T cell Deficiency

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Committee Members:

Nicholas Buchkovich, Major Field Member
Aron Lukacher, Chair & Dissertation Advisor
Todd Schell, Major Field Member
Zissis Chroneos, Outside Unit & Field Member
Ralph Keil, Program Head/Chair

Author:

O'Connor, Michael

Title:

PARP14 regulates cyclin D1 expression to promote cell cycle progression

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

cell cycle
cyclin D1
CDK4/6 inhibitors
CRISPR
PARP14
breast cancer

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Committee Members:

Thomas Spratt, Committee Member & Major Field Represnt
James Broach, Committee Member & Major Field Represnt
Ralph Keil, Committee Member & Major Field Represnt
Lisa Shantz, Committee Member & Related Areas Repres
George Moldovan, Chair & Major Field Represnt
Ralph Keil, Program Head/Chair

Author:

Tang, Tiffany

Title:

Effects of Vertical Sleeve Gastrectomy on Taste Preferences and Underlying Neural Signaling in an Obese Rat Model of Spinal Cord Injury

Graduate Program:

Biomedical Sciences (MS)

Keywords:

spinal cord injury
vertical sleeve gastrectomy
neural mechanisms
obesity
taste preference

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Committee Members:

Andras Hajnal, Thesis Advisor/Co-Advisor
Yuval Silberman, Committee Member
Ralph Keil, Program Head/Chair
Ziaur Rahman, Committee Member

Author:

Manfredi, Barbara

Title:

Effects of schweinfurthin analogue 5’-methylschweinfurthin G in multiple myeloma cell lines

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

multiple myeloma
schweinfurthin G
5’-methylschweinfurthin G
cytotoxicity
natural product
MIP-1α
Golgi secretion
AKT
human-derived cell lines

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Committee Members:

Elizabeth Proctor, Outside Field Member
Kent Vrana, Major Field Member
Raymond Hohl, Chair & Dissertation Advisor
Barbara Miller, Outside Unit Member
Jeffrey Neighbors, Major Field Member
Ralph Keil, Program Head/Chair

Author:

Nduwumwami, Asvelt

Title:

Regulatory Role of Sphingolipid Metabolites in Immunogenic Cancer Cell Death

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Immunogenic cell death
sphingosine kinase
ceramide
sphingolipid metabolism
calreticulin

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Committee Members:

Jong Yun, Chair & Dissertation Advisor
Nadine Hempel, Special Member
Victor Ruiz-Velasco, Outside Unit & Field Member
Jeffrey Neighbors, Major Field Member
Ralph Keil, Program Head/Chair
Arati Sharma, Major Field Member
Jeremy Andrew Hengst, Special Member

Author:

Fike, Adam James

Title:

TRANSCRIPTIONAL REGULATION OF B CELL RESPONSES IN PROTECTION AND AUTOIMMUNITY

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

B cells
Autoimmunity
Germinal Center
Antibody
Immunization
Infection

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Committee Members:

Nicholas Buchkovich, Major Field Member
Aron Lukacher, Major Field Member
Ziaur Rahman, Chair & Dissertation Advisor
Mohamed Trebak, Outside Unit & Field Member
Edward Harhaj, Major Field Member
Ralph Keil, Program Head/Chair