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Author:

Lesko, Elizabeth

Title:

An Investigation of the Spontaneous Regression of Chemically-Induced Neoplastic Skin Lesions in Mice Lacking Autoimmune Regulator

Graduate Program:

Biomedical Sciences (MS)

Keywords:

Autoimmune Regulator
Non-melanoma skin cancer
Squamous Cell Carcinoma
Mouse model
Cancer
Regression
Chemical carcinogenesis

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Committee Members:

Ryan Hobbs, Thesis Advisor/Co-Advisor
Amanda Marie Nelson, Committee Member
Ralph Keil, Program Head/Chair
Lisa M Shantz, Thesis Advisor/Co-Advisor
Christopher Charles Norbury, Committee Member

Author:

Crawford, Lataijah

Title:

Characterization Of Decursinol Efficacy, Tolerance, And Mechanism In Models Of Pain

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

AGN; Angelica gigas Nakai
DOH; Decursinol
CENP; Chemotherapy-evoked neuropathic pain
MOR; Morphine
NXO; Naloxone
TRPA1; Transient receptor potential ankyrin 1
TRPV1
Transient receptor vanilloid receptor 1
TRPV1; Transient receptor vanilloid receptor 1
5-HT2; Serotonin receptor 2
5-HT2A; Serotonin receptor 2A
5-HT2C; Serotonin receptor 2C
CB1; Cannabinoid receptor type 1
CB2; Cannabinoid receptor type 2
WT; Wild-type mouse

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Committee Members:

Junxuan Lu, Outside Field Member
Patricia Grigson Kennedy, Outside Unit Member
Ralph Keil, Program Head/Chair
John Ellis, Major Field Member
Daniel Morgan, Special Member
Lisa Shantz, Chair & Dissertation Advisor

Author:

Liu, Xiaoming

Title:

Mechanisms of resistance to anti-GD2 immunotherapy in neuroblastoma

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Neuroblastoma
Small extracellular vesicles
Tumor microenvironment
NK cells
anti-GD2 immunotherapy
CRISPR screen

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Committee Members:

Vladimir Spiegelman, Major Field Member
Jeffrey Sundstrom, Outside Unit Member
Hong-Gang Wang, Chair & Dissertation Advisor
Todd Schell, Major Field Member
Edward Harhaj, Outside Field Member
Ralph Keil, Program Head/Chair

Author:

Walston, Joshua

Title:

Epstein-Barr virus Glycoproteins BDLF2 and BMRF2 are Important for Efficient Infection and Spread in Oral Epithelia

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

EBV
BDLF2
BMRF2
Cell-to-cell
Stratified Epithelium
Herpesvirus

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Committee Members:

Ralph Keil, Program Head/Chair
Neil Christensen, Major Field Member
Gregory Yochum, Outside Unit & Field Member
Jianming Hu, Major Field Member
Jeffery Sample, Major Field Member
Clare Sample, Chair & Dissertation Advisor

Author:

Hong, Xupeng

Title:

Determinants of HBV Host Tropism and Roles of HBV Precore/Core Proteins

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Hepatitis B Virus
HBV
host tropism
core protein
precore protein
Woodchuck Hepatitis Virus
capsid
cccDNA
infection
replication

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Committee Members:

Jianming Hu, Chair & Dissertation Advisor
John Wills, Major Field Member
Edward Harhaj, Major Field Member
Craig Meyers, Major Field Member
Fang Tian, Outside Unit & Field Member
Ralph Keil, Program Head/Chair
Yuka Imamura Kawasawa, Special Member

Author:

Maglakelidze, Natella

Title:

Role of autoimmune regulator (AIRE) in keratinocyte biology and skin diseases

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Autoimmune regulator
Alopecia Areata
Mouse model
Hair follicle biology
Keratinocyte biology
JAK-STAT signaling
Vitiligo

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Committee Members:

David Degraff, Outside Unit Member
Amanda Nelson, Major Field Member
Ryan Hobbs, Co-Chair & Dissertation Advisor
Joslyn R Sciacca Kirby, Special Member
Lisa Shantz, Co-Chair & Outside Field Member
Ralph Keil, Program Head/Chair

Author:

Manfredi, Barbara

Title:

Effects of schweinfurthin analogue 5’-methylschweinfurthin G in multiple myeloma cell lines

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

multiple myeloma
schweinfurthin G
5’-methylschweinfurthin G
cytotoxicity
natural product
MIP-1α
Golgi secretion
AKT
human-derived cell lines

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Committee Members:

Elizabeth Proctor, Outside Field Member
Kent Vrana, Major Field Member
Raymond Hohl, Chair & Dissertation Advisor
Barbara Miller, Outside Unit Member
Jeffrey Neighbors, Major Field Member
Ralph Keil, Program Head/Chair

Author:

Kendra, Christopher

Title:

A Salmonella Virulence Factor Regulates Second Messenger Signaling and Effector Protein Expression via Proteolysis

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Salmonella
Proteolysis
Cellulose
second messenger
virulence factors

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Committee Members:

Christopher Norbury, Major Field Member
Mauricio Pontes, Co-Chair & Dissertation Advisor
Guy Townsend, Outside Unit Member
Clare Sample, Co-Chair & Outside Field Member
Ralph Keil, Program Head/Chair

Author:

Nduwumwami, Asvelt

Title:

Regulatory Role of Sphingolipid Metabolites in Immunogenic Cancer Cell Death

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

Immunogenic cell death
sphingosine kinase
ceramide
sphingolipid metabolism
calreticulin

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Committee Members:

Jong Yun, Chair & Dissertation Advisor
Nadine Hempel, Special Member
Victor Ruiz-Velasco, Outside Unit & Field Member
Jeffrey Neighbors, Major Field Member
Ralph Keil, Program Head/Chair
Arati Sharma, Major Field Member
Jeremy Andrew Hengst, Special Member

Author:

Fike, Adam James

Title:

TRANSCRIPTIONAL REGULATION OF B CELL RESPONSES IN PROTECTION AND AUTOIMMUNITY

Graduate Program:

Biomedical Sciences (PHD)

Keywords:

B cells
Autoimmunity
Germinal Center
Antibody
Immunization
Infection

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Committee Members:

Nicholas Buchkovich, Major Field Member
Aron Lukacher, Major Field Member
Ziaur Rahman, Chair & Dissertation Advisor
Mohamed Trebak, Outside Unit & Field Member
Edward Harhaj, Major Field Member
Ralph Keil, Program Head/Chair